Platelets
Protocols
PLATELETS
Normal value: 150,000-450,000/cu mm.
THROMBOCYTOPENIA:
(Below 150,000/cu mm)
• Idiopathic thrombocytopenic purpura
• Leukaemia (usually acute leukaemias)
• Aplastic anaemia
• Multiple myeloma
• Hypersplenism
• Drug reactions
• Megaloblastic anaemia.
PLATELETS:
Normal value: 150,000-450,000/cu mm.
THROMBOCYTOSIS:
(Count above 450,000/cu mm)
• Polycythemia vera, essential thrombocythemia
• After splenectomy
• After haemorrhage
• After parturition
• After severe injuries, major surgical operations.
PANCYTOPENIA
When all the three elements of blood are reduced:
• Subleukaemic leukaemia
• Aplastic anaemia
• Bone marrow infiltration, i.e. Hodgkin’s, multiple
myeloma or secondary carcinoma deposit.
• Hypersplenism
• Megaloblastic anaemia
• Disseminated sclerosis.
Marrow
hypoplasia:
Childhood
bone marrow failure
syndromes,
e.g. Fanconi's anaemia,
dyskeratosis
congenita,
amegakaryocytic
thrombocytopenia
• ldiopathic
aplastic anaemia
•
Drug-induced: cytotoxics,
antimetabolites
•
Transfusion-associated graft-versus-
host disease